Biclo - S Ointment contains Clobetasol Propionate & Salicylic Acid Clobetasol is used in adults to treat moderate to severe scalp psoriasis. Clobetasol reduces the swelling, itching and redness that can occur with this condition. This medication is a very strong (super-high-potency) corticosteroid. Topical salicylic acid is also used to treat skin conditions that involve scaling or overgrowth of skin cells such as psoriasis (a skin disease in which red, scaly patches form on some areas of the body), ichthyoses (inborn conditions that cause skin dryness and scaling), dandruff, corns, calluses, and warts etc.